National Heart, Lung, and Blood Institute – Research Projects

CFDA 93.HL2 Active Grant Cooperative Agreement

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$2.77B FY2026
$2.56B
FY24
$2.64B
FY25
$2.77B
FY26*
* estimated

Program Objective

The National Heart, Lung, and Blood Institute (NHLBI) provides global leadership for a research, training, and education program to promote the prevention and treatment of heart, lung, blood, and sleep conditions and enhance the health of all individuals so that they can live longer and more fulfilling lives. NHLBI supports research projects that align with fulfilling the mission of the NHLBI.

Eligibility

Eligible Applicants

  • Local
  • Nonprofit Organization
  • Unrestricted by Individual Type
  • For-Profit Organization
  • Not-for-Profit Organization

Local (includes State-designated Indian Tribes; excludes institutions of higher education and hospitals), Public nonprofit institution/organization (includes institutions of higher education and hospitals), Individual/Family, Small business (less than 500 employees), Private nonprofit institution/organization (includes institutions of higher education and hospitals). Any nonprofit organization engaged in biomedical research and institutions or companies organized for profit may apply for almost any kind of grant. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council.

Beneficiaries

  • Unrestricted by Individual Type
  • For-Profit Organization
  • Nonprofit Organization
  • Health Professional
  • Education Professional

Any nonprofit or for-profit organization, company or institution engaged in biomedical research.

How to Apply

Award Procedure

All accepted applications are evaluated by an appropriate initial review group (study section). All grant applications receive a final secondary review by the National Heart, Lung, and Blood Advisory Council. Staff inform applicants of the results of the review. If support is contemplated, staff initiate preparation of awards for grants.

Decision Timeline

  • Approval: > 180 Days
  • Renewal interval: > 180 Days

Regular Grants: From 7 to 9 months.

Program details & compliance

Description

The National Heart, Lung, and Blood Institute (NHLBI) provides global leadership for a research, training, and education program to promote the prevention and treatment of heart, lung, blood, and sleep conditions and enhance the health of all individuals so that they can live longer and more fulfilling lives. NHLBI supports research projects that align with fulfilling the mission of the NHLBI.

Mission Categories

Primary: Prevention and Control (includes Suicide Prevention)

Use of Funds

Allowed Uses

Grants may support stipends, research expenses, supplies, travel, childcare costs, and research training tuition as required to perform the research effort.

Restrictions

Restrictions or limitations are imposed against the use of funds for entertainment, foreign travel, general-purpose equipment, alterations and renovations, and other items not regularly required for the performance of research.

Required Documentation

Costs will be determined in accordance with OMB Circular No. A-87 for State and local governments. For-profit organization costs are determined in accordance with Subpart 31.2 of the Federal Acquisition Regulations. For other grantees, costs will be determined in accordance with DHHS Regulations 45 CFR, Part 74, Subpart Q. Electronic submission of NIH Research Performance Progress Reports (RPPR) applies to non-competing continuations. OMB Circular No. A-87 applies to this program. 2 CFR 200, Subpart E - Cost Principles applies to this program. 2 CFR 200, Subpart E - Cost Principles applies to this program. 2 CFR 200, Subpart E - Cost Principles applies to this program.
2 CFR 200, Subpart E - Cost Principles applies to this program.

Reporting & Compliance

Audit Required
Yes — Determined at Time of Award
Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Kelly Barford
301.594.4600
National Heart, Lung, and Blood Institute (NHLBI), Bethesda, MD 20817
Christine Cullinane — NHLBI Referral Officer
3018277944
National Heart, Lung, and Blood Institute (NHLBI), Bethesda, MD 20817
Data from SAM.gov Federal Assistance Listings. Source published: 2026-01-30. Spec v2.0. Last synced: 2026-05-29 05:39:18.