Human Genome Research – Other Research

National Human Genome Research Institute - Other Research
CFDA 93.HG3 Active Grant Cooperative Agreement

Program Funding

Annual program obligations reported to SAM.gov.

Latest annual funding (estimated)
$149.3M FY2026
$120.7M
FY24
$109.4M
FY25
$149.3M
FY26*
* estimated

Funded Projects

Examples of what this program has supported.

FY2025 In FY 2025, over $100M was obligated for other research-related projects, including developmental genomic tissue expression, functional mapping, reactome and gene ontology, RNA-binding proteins, and developing toolkits for research. Other research-related projects supported by NHGRI in FY 2025 include those found on this list:
https://reporter.nih.gov/search/Un_koXtT5keK6GI1wwcE_A/projects?shared=true
FY2026 Current active other-related research projects supported by NHGRI include technology development coordinating centers, protein sequence and function resources, genomics conferences, genome databases, and those found on this list: https://reporter.nih.gov/search/44jIpAg9okKRFgCuFWgVPg/projects?shared=true

Program Objective

As a leading authority in the field of genomics, the mission of the National Human Genome Research Institute (NHGRI) is to accelerate scientific and medical breakthroughs that improve human health by driving cutting-edge research, developing new technologies, and studying the impact of genomics on society. Congress initially established NHGRI to characterize the structure and function of the human genome, including the mapping and sequencing of individual genes. This also includes reviewing and funding genomics research proposals, developing training programs, coordinating international genome research, communicating advances in genome science to the public, and reviewing and funding proposals to address the ethical and legal issues associated with this research. NHGRI supports the development of methods, resources, and technologies to improve the health of all humans through advances in genomics research. NHGRI supports research that accelerates foundational resources, technology development, and experimental and computational approaches for basic genomics and functional genomics research; for the application of genomics to medical science and clinical care; and to support ethical, legal and social implications (ELSI) research concerning societal issues that need to be addressed as genomic science advances.

Eligibility

Eligible Applicants

  • U.S. Federal Government
  • U.S. State Government
  • U.S. Territory Government
  • Department/Agency of U.S. State
  • Department/Agency of U.S. Territorial Gov
  • Federally Recognized Tribal Government
  • Municipality/Township Government
  • County Government
  • Local Government Consortium
  • Public Housing Authority
  • Foreign Nonprofit Organization
  • Foreign Not-for-Profit Organization
  • Foreign For-Profit Organization
  • International Organization
  • Nonprofit Organization
  • Not-for-Profit Organization
  • For-Profit Organization

Awards can be made to any public or private, for-profit or nonprofit university; college; medical, dental, nursing school; school of public health; hospital; laboratory; or other institution; state and local health departments; other public or private institutions, both for-profit and non-profit; and/or to individuals. Any additional eligibility requirements are described at the NOFO level.

Beneficiaries

  • Specific Restrictions (Determined at NOFO Level)

How to Apply

Award Procedure

Only applications submitted in response to a Notice of Funding Opportunity (NOFO) will be considered for funding. Each application is scientifically reviewed by subject matter experts, with competing applications going through initial peer review and secondary review by an advisory council. All scored applications compete for available funds on the basis of scientific and technical merit, program relevance, program balance among aras of research, and availability of funds. Awards are issued throughout the year by the National Human Genome Research Institute (NHGRI).

Contact NIH staff using information at the NOFO level with any questions.

Decision Timeline

  • Approval: > 180 Days

From submission to award of funds: about 6 to 9 months.

Program details & compliance

Description

The National Human Genome Research Institute supports: (1) the development of genomic resources, technologies, and methods in basic genomics, functional genomics, and genomic computational and data science research that are generally applicable to biomedical research; (2) efforts to advance the application of genomics to medical science and clinical care; and (3) studies to understand the ethical, legal, social implications of genomics research for individuals and populations. NHGRI also develops and supports initiatives that expand opportunities for genomics education and careers and cultivates genomics training programs.

The Other Research mechanism includes 1) Research Career Programs, 2) Cooperative Clinical Research, 3) Biomedical Research Support, and 4) Other Research Related. Other Research mechanism projects include the following activity codes: all the activity codes that begin with K (i.e., K01, K08), R10, U10, U50, UG1, S10, D43, D71, F99, OT2, P2C, R13, R24, R25, U24, and U2C.

Mission Categories

Primary: Research and Development

Other categories:
General Health and MedicalHigher EducationMedical EducationBiology

Use of Funds

Allowed Uses

Grants are awarded to an eligible institution in the name of a principal investigator for a discrete project or group of related projects representing the investigator's interest and competence. Funds may be used for salaries and wages, equipment, supplies, travel and other allowable costs required to carry out the research project. Awardees agree to administer awards in accordance with the regulations and policies governing research assistance programs in the Public Health Service Act, as stated in the NIH Grants Policy Statement and the terms and conditions in the notice of award. Any additional information is described at the NOFO level.

Restrictions

Awardees agree to administer awards in accordance with the regulations and policies governing research assistance programs in the Public Health Service Act, as stated in NIH Grants Policy Statement and the terms and conditions, in the notice of award.

Any additional information is described at the NOFO level.

Required Documentation

Applicants should submit electronically via Grants.gov as directed in the relevant NIH Funding Opportunity Announcement. All required forms specified in the application kit are to be completed by the applicant and submitted with the application package.

For-profit organizations' costs are determined in accordance with 48 CFR, Subpart 31.2 of the Federal Acquisition Regulations.

For other grantees, costs will be determined by HHS Regulations, 45 CFR, Part 74, Subpart Q.

Reporting & Compliance

Audit Required
Yes — Determined at Time of Award, Ad-hoc
Records Retention
3 years

Applicable 2 CFR 200 Subparts

  • Subpart B — General Provisions
  • Subpart C — Pre-Federal Award Requirements
  • Subpart D — Post-Federal Award Requirements
  • Subpart E — Cost Principles
  • Subpart F — Audit Requirements

Contacts

Issel Anne Lim, PhD
301-648-8106
6700B Rockledge Drive, Suite 3100, Bethesda, MD 20817
NHGRI Research Funding Team
301-402-6352
6700B Rockledge Drive, Suite 3100, Bethesda, MD 20817
Data from SAM.gov Federal Assistance Listings. Source published: 2026-01-30. Spec v2.0. Last synced: 2026-05-29 05:39:34.