Flexible Funding Model-Infrastructure Development and Maintenance for State Manufactured Food Regulatory Programs (U2F) Clinical Trials Not Allowed
🏛 Food and Drug Administration (HHS-FDA)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for state and territorial manufactured food regulatory programs seeking federal support for food safety infrastructure. Eligible applicants include state agencies, state-recognized tribal organizations, and U.S. territories that operate food regulatory programs. Programs can apply for one or more of four tracks: MFRPS development/maintenance, Food Protection Task Force support, dietary supplement program development, or special food safety projects.
Funding supports infrastructure, personnel, training, and program development activities that align with the Integrated Food Safety System (IFSS) framework. Applicants must demonstrate commitment to advancing food safety standards and collaboration across federal, state, local, tribal, and industry partners. Clinical trials are not allowable.
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Program description
The intended outcome of this Notice of Funding Opportunity (NOFO) is to advance efforts for a nationally Integrated Food Safety System (IFSS) by supporting Manufactured Food Regulatory Program Standards (MFRPS), Food Protection Task Force (FPTF) programs, Dietary Supplement (DS) programs, and special projects. For the purposes of this NOFO, the term state encompasses all eligible organizations as defined in Section 3.
MFRPS Development or Maintenance:
The purpose of this Notice of Funding Opportunity (NOFO) section is to advance efforts for a nationally Integrated Food Safety System (IFSS) by assisting state manufactured food regulatory programs to achieve and maintain conformance with the most current version of the Manufactured Food Regulatory Program Standards (MFRPS). The MFRPS are intended to ensure that state manufactured food regulatory programs implement a high-quality regulatory program through the development and maintenance of a regulatory framework that builds on and emphasizes mutual reliance with all programs. Also, the program standards are intended to enhance food safety by establishing a uniform basis for measuring and improving the performance of manufactured food regulatory programs in the United States. Conformance with these program standards will help federal and state programs better direct their regulatory activities at reducing foodborne illness hazards in plants that manufacture, process, pack, or hold foods.
Food Protection Task Force (FPTF):
The purpose of this funding option is to establish and/or support a Food Protection Task Force (FPTF) with diverse membership representative of stakeholders across the state that is responsible for promoting the integration of an efficient statewide human and animal food (HAF) protection system that addresses state and region-specific needs and that maximize the protection of the public health. These efforts include: establishing a food safety/protection network of subject matter experts, fostering educational opportunities, developing replicable resources and systematically fostering communication, education, outreach, cooperation and collaboration within the states among federal, state, local, tribal and territorial HAF protection, public health, agriculture, and regulatory agencies, industry, academia, and consumers to initiate and/or support HAF protection activities to improve public health.
A strong FPTF can also help improve human and animal food emergency surveillance, response, and post-response systems by focusing on preparedness, building strong communication channels, and establishing relationships with key players before food-related incidents occur.
Dietary Supplements:
The goal of this funding option is to facilitate the development of state driven dietary supplement regulatory framework and programs. The overall objective of this funding opportunity is to advance the adoption and implementation of the cGMPs for Dietary Supplements Rule codified at 21 CFR Part 111. Specifically, this track will provide funding support for dietary supplement training and program development activities.
Special Projects:
The purpose of this funding option is to develop and implement special projects that support innovation and integration in a IFSS using the MFRPS framework. This track will support other emerging food safety priorities that develop over the lifespan of the project. State programs will be expected to share project deliverables and resources developed with other programs.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (Application for Federal Assistance)
- Project Narrative and Statement of Work
- Budget and Budget Justification
- Organizational Capability Statement
- Letters of Commitment from partners
- Documentation of current state food regulatory program status
Program contact
- 👤 Terrin Brown Grantor
- 📧 terrin.brown@fda.hhs.gov
- 📞 (240) 402-7610
Funding track record
Recent awards under CFDA 93.103 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$121,795,918
-
$76,105,626
-
$50,217,964
-
$47,940,304
-
$36,000,000
-
$35,573,997
-
$35,391,995
-
$30,732,300
-
$23,332,999
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$21,347,288
Top States by Funding
- AZ 3 awards $131.4M
- MD 7 awards $108.7M
- CA 9 awards $106.5M
- VA 5 awards $96.6M
- PA 10 awards $77.4M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.103). How funding has trended year over year.
| 2016 | $170,482,435 | |
| 2017 est. | $208,900,832 | |
| 2018 | $173,077,408 | |
| 2019 | $198,507,896 | |
| 2020 | $212,448,590 | |
| 2021 | $218,918,739 | |
| 2022 est. | $255,910,458 | |
| 2023 est. | $246,894,600 |
FAQ
Who is eligible to apply for this grant?
State and territorial food regulatory agencies, and state-recognized tribal organizations operating food regulatory programs. Applicants must oversee manufactured food, dietary supplement, or related food protection activities.
What funding tracks are available?
Four options: MFRPS development/maintenance, Food Protection Task Force establishment, dietary supplement program development, or special food safety innovation projects. Applicants can pursue one or multiple tracks.
What can funding be used for?
Personnel, training, program development, infrastructure improvements, and collaborative activities. Equipment, travel, and contractual services are typically allowable. Clinical trials are not permitted.
What is the award range?
Awards typically range from $340,000 to $1,285,000 depending on application scope, state capacity needs, and project focus area.
Is cost-sharing required?
No cost-sharing requirement. This is 100% federal funding with no required match from applicant organizations.
💡 Tips for applicants
- Align your project narrative directly to the Integrated Food Safety System (IFSS) framework and MFRPS standards. Show how your activities strengthen food safety infrastructure.
- If pursuing the Food Protection Task Force track, demonstrate broad stakeholder engagement from federal, state, local, tribal, and industry partners. Name specific collaborators and describe communication structures.
- Be specific about current gaps in your state's food regulatory program. Reference the most current MFRPS version and explain which standards you are working toward.
- Include measurable outcomes and timelines. Reviewers expect clear metrics for training completion, conformance improvements, or new regulations implemented.
- Emphasize innovation and replicability for special projects. Show how your deliverables and resources can benefit other states and the national food safety system.
⚠️ Common mistakes
Vague connection to IFSS or MFRPS standards leads to weak scoring. Projects that lack measurable outcomes or timelines struggle in review. Failure to demonstrate meaningful state and federal partner collaboration weakens competitiveness.
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