Notice of Intent to Issue DE-FOA-0003647 Accelerating Scale-up and Pre-piloting of Emerging Chemical Technologies (ASPECT)
🏛 Golden Field Office
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for entities conducting research and development on emerging chemical technologies. Federal laboratories, private companies, nonprofits, universities, and consortia may be eligible. Work must focus on producing chemicals from alternative or waste feedstocks, with the goal of scaling up novel technologies.
Activities supported include research, development, and scale-up of technologies for chemicals from alternative feedstocks. Projects must address domestic supply chain resiliency, cost reduction, or environmental safety benefits. Both conventional and bio-advantaged chemicals are eligible.
Geographic scope is national. The U.S. Department of Energy will issue a formal Notice of Funding Opportunity (NOFO) in the future with full eligibility details. Interested parties should monitor eere-exchange.energy.gov for the official announcement.
⚖️ Cost sharing / matching required — applicants must contribute their own funds.
Not the right fit? Find grants for your organization in 5 questions →
Program description
CMEI intends to issue, on behalf of AFFO, a NOFO titled, “Accelerating Scale-up and Pre-piloting of Emerging Chemical Technologies (ASPECT).” This NOFO will seek applications for financial assistance from entities that wish to conduct work in support of AFFO’s focus on emerging chemical technologies. AFFO supports expanding the supply and use of domestic alternative feedstocks to improve supply chain resiliency of U.S. chemical production and to expand domestic manufacturing through technology innovation to lower costs and improve environmental safety of chemical production.[1]
Through this NOFO, AFFO seeks to support research, development, and scale-up of novel technologies for producing chemicals from alternative and waste feedstocks. Chemicals of interest include foundational molecules that can be further transformed into high-value end-products, chemical compounds or derivatives generated either from these foundational molecules or directly from alternative feedstocks through process intensification, as well as final end-products. This NOFO will aim to support work involving chemicals that offer advantages in terms of performance or cost, or that offer benefits to America’s foreign trade or national security. The proposed chemicals can be either conventional or bio-advantaged chemicals. Conventional chemicals must possess added benefits like improved domestic supply chain resiliency, reduced U.S. imports, reduced cost, or large market growth potential. Bio-advantaged chemicals must possess favorable properties—such as enhanced durability, production efficiency, or decreased toxicity—that create new value propositions.
This Notice of Intent (NOI) is for informational purposes only; DOE is not requesting comments or applications at this time. All information provided here is subject to change. This notice serves to inform interested parties that the U.S. Department of Energy (DOE) may issue a Notice of Funding Opportunity (NOFO). Please be aware that any future NOFO could differ significantly from what is described here, or one may not be issued at all. DOE will provide a designated channel for questions once a NOFO is officially released.
This Notice of Intent can be viewed by visiting eere-exchange.energy.gov.
[1]Energy Policy Act (EPAct) 2005, Pub. L. 109-58, § 931 as codified at 42 U.S.C. § 16231; EPAct 2005 § 932, as codified at 42 U.S.C § 16232.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- Official NOFO (not yet released)
- Full eligibility and application requirements TBD
- Check eere-exchange.energy.gov when NOFO issues for complete submission requirements
Program contact
- 👤 Golden Field Office
- 📧 ryan.mccleary@doe.gov
- 📞 2022871878
Funding track record
Recent awards under CFDA 81.087 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$292,505,705
-
$141,695,691
-
Avapco Llc GA$100,000,000
-
$69,520,898
-
$66,736,496
-
$65,645,481
-
$49,550,000
-
$42,681,706
-
$41,186,672
-
Verdagy Inc CA$39,633,303
Top States by Funding
- UT 3 awards $348.9M
- NY 10 awards $300.8M
- OR 7 awards $251.4M
- CA 14 awards $220.3M
- WA 7 awards $110.3M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 81.087). How funding has trended year over year.
| 2023 | $437,332,515 | |
| 2024 est. | $1,079,663,502 | |
| 2025 est. | $393,848,860 |
FAQ
When will the full Notice of Funding Opportunity be released?
This is a Notice of Intent only. DOE will issue the formal NOFO at a future date with a deadline of September 14, 2026. Check eere-exchange.energy.gov for updates.
Who is eligible to apply?
Specific eligibility requirements will be detailed in the full NOFO. Typically, federal labs, universities, nonprofits, and private companies can apply to DOE grants. Watch for the official announcement for exact criteria.
What types of chemicals are supported?
Projects must develop chemicals from alternative or waste feedstocks. Both conventional chemicals (with domestic supply benefits) and bio-advantaged chemicals (with enhanced properties) qualify.
Is cost-sharing required?
Yes, cost-sharing is required. The specific percentage will be stated in the formal NOFO.
Can I get more information now?
Limited details are available. This is a Notice of Intent for informational purposes only. DOE will provide a question channel once the formal NOFO is released.
💡 Tips for applicants
- Monitor eere-exchange.energy.gov regularly starting now. The formal NOFO will appear there with full details and application instructions.
- Begin identifying your technology, alternative feedstock sources, and manufacturing scale-up plan now. These are core to competitive proposals.
- Build partnerships early if needed. Consortia involving industry, universities, and labs often strengthen DOE applications.
- Document your chemical's advantages: cost savings, supply chain benefits, environmental safety improvements, or national security value.
- Review past DOE-EERE awards and final project reports for similar technologies. They show what funders prioritize and typical project structures.
⚠️ Common mistakes
Proposals that focus only on basic research without a clear path to commercialization or scale-up often score poorly. This program emphasizes development and pre-piloting stages. Weak justification for why the chemical offers domestic supply chain, cost, or environmental benefits fails to address program priorities. Insufficient detail on the scale-up or manufacturing plan makes reviewers doubt feasibility.
Similar grants
- OPEN SEEDING CRITICAL ADVANCES FOR LEADING ENERGY TECHNOLOGIES WITH UNTAPPED POTENTIAL (SCALEUP) READY — Advanced Research Projects Agency Energy
- CLOSING SOON Critical Minerals and Materials Accelerator Notice of Funding Opportunity — Golden Field Office
- OPEN Chemical Oceanography — U.S. National Science Foundation
- ROLLING Collaborations to Enhance Drug Development and Regulatory Science — Food and Drug Administration
- OPEN Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed) — National Institutes of Health