Asthma and Allergic Diseases Cooperative Research Centers
🏛 National Institutes of Health (HHS-NIH11)
✓ Free, no account · Source: Grants.gov · Last verified Jul 15, 2026
Can you apply?
This grant is for research institutions and medical centers conducting multi-center, multidisciplinary translational research in asthma and allergic diseases. Applicants must propose collaborative research addressing disease mechanisms, clinical trials, observational studies, or immune pathway projects using human materials. The program supports institutions capable of leading multi-center networks studying asthma, food/drug allergies, atopic dermatitis, and related allergic/inflammatory conditions.
Eligible organizations typically include academic medical centers, research universities, and NIH-recognized institutions with established research infrastructure. Teams must demonstrate capacity for clinical and basic research collaboration across multiple sites. Projects should focus on understanding disease onset, progression, treatment modalities, and treatment response mechanisms.
Geographic scope is national. International collaborators may participate as part of a U.S.-led consortium. Applicants should review NIH guidelines for cooperative agreements and NIAID-specific requirements before submitting.
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Key dates
- Jun 24, 2026 Applications open
- May 21, 2027 Application deadline in 309 days
- Mar 1, 2028 Award announced
- Mar 1, 2028 Project start
Program description
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Asthma and Allergic Diseases Cooperative Research Centers (AADCRC). The AADCRC program serves as the cornerstone of NIAID’s efforts to promote clinical and basic research in diseases including asthma, upper airway allergic/inflammatory diseases, food and drug allergies, atopic dermatitis, and other allergic diseases. The overarching goals of this program are to investigate mechanisms underlying the onset, progression, treatment modalities, and mechanisms of treatment response for the diseases of interest. Goals of the program may include exploring disease mechanisms and/or treatment modalities in small clinical trials/observational studies or immune pathway-focused projects using primarily human materials. The AADCRC is the only NIAID program that is designed to promote multi-center, multidisciplinary, translational research in asthma and allergic diseases. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R)
- Project Narrative (Research Strategy)
- Specific Aims
- Research Design and Methods
- Budget and Budget Narrative
- Biographical Sketches (Key Personnel)
- Letters of Commitment (Collaborating Institutions)
- NIH Biographical Sketch (Form Page 5)
Program contact
- 👤 Division of Allergy, Immunology, and Transplantation AADCRC Program Group
- 📧 AADCRC_U19@mail.nih.gov
- 📞 Please contact via email.
Funding track record
Recent awards under CFDA 93.855 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$246,626,852
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$201,437,825
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$185,816,804
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$180,737,624
-
$136,265,880
-
$116,817,868
-
$93,394,862
-
$89,845,851
-
$74,456,241
-
$72,987,380
Top States by Funding
- CA 8 awards $696.2M
- MA 6 awards $602.8M
- NY 6 awards $335.0M
- TX 3 awards $280.9M
- GA 5 awards $257.9M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.855). How funding has trended year over year.
| 2024 | $4,073,812,529 | |
| 2025 | $4,378,235,639 | |
| 2026 est. | $4,299,426,996 |
FAQ
What types of research does this program fund?
The program supports translational research in asthma, food/drug allergies, atopic dermatitis, and allergic diseases. Projects may include small clinical trials, observational studies, or immune pathway investigations using human materials.
Can single-site institutions apply?
This is a multi-center cooperative program. Applicants should be prepared to lead or participate in collaborative research networks across multiple institutions.
What is the deadline and funding timeline?
The deadline is May 21, 2027. NIH typically funds projects for 5 years under cooperative agreements; check the Funding Opportunity Announcement for specific project period details.
How competitive is this program?
This is a highly specialized program. Strong applications include preliminary data, established multi-center partnerships, and clear translational pathways from basic to clinical research.
Is cost-sharing required?
No cost-sharing is required for this grant. However, institutions must demonstrate institutional commitment through other means.
💡 Tips for applicants
- Establish multi-center partnerships early. Identify collaborating institutions and document their commitment letters before application.
- Show preliminary data demonstrating feasibility. Even pilot studies strengthen competitiveness for translational research programs.
- Clearly connect basic and clinical research. Explain how your project bridges laboratory findings to patient care and disease understanding.
- Follow NIH cooperative agreement format requirements. These differ from standard R01 grants; review the FOA carefully for submission structure.
- Align with NIAID priorities. Address disease mechanisms, treatment response, or specific allergic/inflammatory diseases listed in the program scope.
⚠️ Common mistakes
Underestimating the multi-center requirement. Single-site or primarily single-site applications fail to meet program design intent. Weak or missing preliminary data reduces confidence in project feasibility. Unclear connection between basic research aims and clinical relevance or patient outcomes.
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