DoW Peer Reviewed Medical, Impact Award
🏛 Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA)
✓ Free, no account · Source: Grants.gov · Last verified Jul 27, 2026
Can you apply?
This grant is for researchers at eligible U.S. organizations conducting applied medical research with near-term clinical impact. Applicants must align projects to congressionally directed FY26 PRMRP topic areas and portfolio-specific strategic goals. Multiple principal investigators from different organizations can participate, with coordinated applications submitted by each PI's institution.
Research must be use-inspired and practice-oriented, translating basic research findings toward clinical solutions. The maximum project duration is 4 years. Awards are funded through cooperative agreements or grants.
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Program description
Summary: The fiscal year 2026 (FY26) Peer Reviewed Medical Research Program (PRMRP) Impact Award supports applied research, defined as use-inspired and practice-oriented science that brings together outcomes from basic research, and insights from the real-world environment, to foster clinical applicability. The Impact Award intends to translate the fundamental understanding of underlying mechanisms toward solutions that have the potential for major near-term impact for patients and clear alignment to one of the congressionally directed FY26 PRMRP topic areas and one of the FY26 PRMRP portfolio-specific strategic goals.
Distinctive Features: This funding mechanism allows for multiple Principal Investigators (PIs). Only the initiating PI’s organization will submit a pre-application, but all PIs’ organizations will need to submit full applications. The partnering PI’s application is an abbreviated package specific to their distinct portion of the research project. Be advised, all associated applications for a research project may be withdrawn if the initiating or partnering application is rejected or administratively withdrawn.
Funding Details: The Congressionally Directed Medical Research Programs (CDMRP) expects to allot roughly $32.0M to fund approximately 10 Impact Award applications with total cost caps of $2.8M for the Single PI Option, or $3.6M for the Partnering PI Option. The maximum period of performance is 4 years. It is anticipated that awards made from this FY26 funding opportunity will be funded with FY26 funds, which will expire for use on September 30, 2032. Awards supported with FY26 funds will be made no later than September 30, 2027.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- Pre-application (initiating PI's organization only)
- Project narrative/proposal
- Budget and budget narrative
- Biographical sketches of all PIs
- Institutional commitment letters
- Letters of support (if applicable)
- Research plan with milestones
Program contact
- 👤 Christopher L Baker Grants Officer
- 📧 help@eBRAP.org
- 📞 3016192332
Funding track record
Recent awards under CFDA 12.420 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
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$2,265,729,366
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$800,631,761
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$74,531,880
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$67,205,571
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$55,443,120
-
$34,191,124
-
$24,783,894
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$21,394,379
-
$19,100,256
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$19,002,641
Top States by Funding
- MD 10 awards $3,150.1M
- NC 11 awards $132.3M
- CA 12 awards $107.3M
- FL 8 awards $99.8M
- MA 8 awards $83.2M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 12.420). How funding has trended year over year.
| 2024 | $1,483,968,520 | |
| 2025 | $1,201,153,417 |
FAQ
What types of organizations can apply?
Eligible organizations include academic institutions, research hospitals, nonprofits, and government agencies. Check the CDMRP website for your organization's specific eligibility status.
Can I apply with multiple principal investigators?
Yes, multiple PIs from different institutions can partner. Each PI's organization submits a full application, but only the initiating PI submits a pre-application.
What is the funding amount?
Single PI projects can request up to $2.8M total cost. Partnering PI projects can request up to $3.6M total cost over the 4-year period.
Is there a letter of intent or pre-application required?
Yes, a pre-application is required from the initiating PI's organization only. Partnering PIs submit full applications directly.
What happens if my application is rejected?
If the initiating or any partnering PI's application is rejected, all associated applications for that research project may be withdrawn.
💡 Tips for applicants
- Ensure your project aligns explicitly to a congressionally directed FY26 PRMRP topic area and a portfolio-specific strategic goal. Misalignment is a common rejection reason.
- For multi-PI projects, establish clear roles and budget allocations between institutions before submission. Confusion about PI responsibilities causes delays.
- Focus on translational and clinical applicability, not basic science alone. This award emphasizes near-term patient impact over fundamental mechanisms.
- Review all FY26 PRMRP guidance documents thoroughly before drafting. Topic areas and strategic goals change annually and drive reviewer evaluation.
- Submit your pre-application and full applications well before the deadline. CDMRP systems can experience high traffic near the cutoff date.
⚠️ Common mistakes
Proposals focused on basic research without clear clinical translation pathway. Misalignment with congressionally directed FY26 PRMRP topic areas or portfolio-specific strategic goals. Multi-PI projects lacking clear coordination and distinct roles between institutions.
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