Advancing Global Health
🏛 Bureau of Global Health Security and Diplomacy
Can you apply?
This grant is for organizations working to strengthen global health systems and address international health threats. Eligible applicants include U.S.-based nonprofits, universities, and public health institutions with experience in global health programs. Activities supported include capacity-building for health workers, disease surveillance systems, and pandemic preparedness initiatives in lower-income countries. Applicants should have demonstrated expertise in international health partnerships and commitment to host-country collaboration.
Geographic scope includes developing nations and regions with significant health security gaps. Priority countries may be specified in the Notice of Funding Opportunity. Domestic activities must directly support global health outcomes abroad.
Applicants must be U.S. entities registered with SAM.gov. Foreign organizations may participate as subcontractors only. The grant requires a 501(c)(3) status or equivalent government agency designation.
This grant is for organizations working to strengthen global health systems and address international health threats. Eligible applicants include U.S.-based nonprofits, universities, and public health institutions with experience in global health programs. Activities supported include capacity-building for health workers, disease surveillance systems, and pandemic preparedness initiatives in lower-income countries. Applicants should have demonstrated expertise in international health partnerships and commitment to host-country collaboration.
Geographic scope includes developing nations and regions with significant health security gaps. Priority countries may be specified in the Notice of Funding Opportunity. Domestic activities must directly support global health outcomes abroad.
Applicants must be U.S. entities registered with SAM.gov. Foreign organizations may participate as subcontractors only. The grant requires a 501(c)(3) status or equivalent government agency designation.
Program description
The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.
Who can apply
Eligible applicants
Details
This grant is for organizations working to strengthen global health systems and address international health threats. Eligible applicants include U.S.-based nonprofits, universities, and public health institutions with experience in global health programs. Activities supported include capacity-building for health workers, disease surveillance systems, and pandemic preparedness initiatives in lower-income countries. Applicants should have demonstrated expertise in international health partnerships and commitment to host-country collaboration.
Geographic scope includes developing nations and regions with significant health security gaps. Priority countries may be specified in the Notice of Funding Opportunity. Domestic activities must directly support global health outcomes abroad.
Applicants must be U.S. entities registered with SAM.gov. Foreign organizations may participate as subcontractors only. The grant requires a 501(c)(3) status or equivalent government agency designation.
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (Application for Federal Assistance)
- Project Narrative (not to exceed 20 pages)
- Detailed Budget and Budget Narrative
- Organizational Capacity Statement
- Letters of Commitment from partner institutions
- Evaluation Plan
- Host-country government approval letters (if applicable)
Program contact
- 👤 Bureau of Global Health Security and Diplomacy
- 📞 771-204-0446
Funding track record
Recent awards under CFDA 19.029 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$260,479,713
-
$188,156,394
-
$150,000,000
-
$75,278,121
-
$38,339,677
-
$589,000
-
$250,000
-
$187,000
-
$180,000
-
$160,000
Top States by Funding
- MD 1 awards $188.2M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 19.029). How funding has trended year over year.
| 2018 | $4,298,067 | |
| 2019 est. | $220,272 | |
| 2021 est. | $1,481,249 |
FAQ
Who is eligible to apply for this grant?
U.S. nonprofits, universities, public health agencies, and government institutions with global health experience can apply. Foreign organizations cannot be prime applicants but may serve as subcontractors.
What is the application deadline?
The deadline is February 14, 2027. Applications open April 30, 2026. Plan for 6-8 months of preparation.
What types of activities does this grant support?
Eligible activities include health worker training, disease surveillance, laboratory strengthening, pandemic preparedness, and health system capacity-building in resource-limited settings.
How competitive is this grant?
This is a highly competitive federal grant. Expect strong applications from major universities and established global health organizations. International partnerships and evidence-based approaches are essential.
What is the typical funding range?
Awards typically range from $500,000 to $3 million annually, depending on scope and geographic scale. Multi-year awards are common.
💡 Tips for applicants
- Start with a clear theory of change linking activities to specific health security outcomes in your target countries.
- Establish formal partnerships with host-country institutions before applying; joint letters of commitment are expected.
- Use recent epidemiological data and needs assessments to justify country/region selection and approach.
- Budget generously for local hiring and host-country institution strengthening; this demonstrates genuine capacity-building commitment.
- Address sustainability explicitly: explain how systems and skills will persist after federal funding ends.
⚠️ Common mistakes
Applying without formal host-country partnerships. Applications perceived as "donor-driven" rather than collaborative fail. Weak sustainability plans that don't explain long-term local ownership. Failing to align activities with stated U.S. diplomatic health security priorities.
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