Autoimmune Diseases Statistical and Clinical Coordinating Center (AD-SCCC)
Can you apply?
This grant is for research institutions and organizations conducting autoimmune disease research and clinical studies. Eligible applicants typically include universities, medical centers, research hospitals, and nonprofit research organizations with strong track records in clinical research. The grant supports the establishment of statistical and clinical coordinating centers that provide infrastructure and services for multi-site autoimmune disease research networks. Applicants must demonstrate capacity to manage complex data systems, coordinate multi-site studies, and provide statistical support to research teams.
Geographic scope is national, though the center will coordinate research across multiple sites. Funded activities include statistical analysis, data management, clinical coordination, and study management for autoimmune disease research initiatives.
Key dates
- Dec 4, 2025 Applications open
- Jun 4, 2026 Application deadline
- Mar 1, 2027 Award announced
- Mar 1, 2027 Project start
Program description
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by establishing an Autoimmune Diseases Statistical & Clinical Coordinating Center (AD-SCCC). The AD-SCCC will provide clinical study development, support domestic and international regulatory requirements, site monitoring, repository management, manuscript production, study archiving, and biostatistical support for ongoing and future clinical trials in the areas of autoimmune diseases, mucosal immunology, and primary immune deficiencies. Additional tasks include collaboration with the Division of Allergy, Immunology and Transplantation (DAIT) Clinical Data and Safety Management Center (CDSMC) and may include support on an emergent basis for other networks and clinical trials within the NIAID mission. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Who can apply
Eligible applicants
How to apply
Application links
Key dates & requirements
Required documents
- SF-424 (R&R) Application Form
- Project Narrative (Research Strategy)
- Budget and Budget Justification
- Biographical Sketches (Key Personnel)
- Facilities and Administrative Resources
- Letters of Support (from participating research sites)
- Data Management Plan
- Organizational Capacity Documentation
Program contact
- 👤 Jeffrey Rice, Ph.D.
- 📧 jeffrey.rice@nih.gov
- 📞 240-627-3552
Funding track record
Recent awards under CFDA 93.855 from the last 3 years — real organizations that won funding through this same program.
Top 10 Largest Recent Awards
-
$438,527,853
-
$246,626,852
-
$204,359,786
-
$201,437,825
-
$200,221,259
-
$185,816,804
-
$180,737,624
-
$136,265,880
-
$116,817,868
-
$99,478,296
Top States by Funding
- CA 10 awards $818.8M
- WA 3 awards $684.0M
- MA 6 awards $602.8M
- NC 3 awards $446.4M
- NY 7 awards $375.8M
Source: USAspending.gov — federal spending transparency. Data covers last 3 years.
Funding history
Annual funding for this program — Federal obligations (CFDA 93.855). How funding has trended year over year.
| 2024 | $4,073,812,529 | |
| 2025 | $4,378,235,639 | |
| 2026 est. | $4,299,426,996 |
FAQ
Who can apply for this grant?
Research universities, medical centers, hospitals, and nonprofit research organizations with established research infrastructure. Academic medical centers with experience managing multi-site studies are competitive candidates.
What types of activities are supported?
Statistical coordination, data management systems, clinical research support, and study management for autoimmune disease research networks.
What is the typical funding range?
NIH U-series awards vary widely. Check the NIH NOT announcement for this specific RFP to confirm budget limits and guidance.
How competitive is this grant?
Very competitive. The grant requires demonstrated experience with multi-site research coordination, strong biostatistical expertise, and prior success managing large clinical databases.
When is the application deadline?
Check the NIH grants.gov listing for the specific deadline date. The application opens December 4, 2025.
💡 Tips for applicants
- Clearly demonstrate your institution's experience managing complex multi-site research networks and large clinical datasets. Highlight past successful coordinating center projects.
- Build a strong team with biostatisticians, clinical coordinators, and IT specialists experienced in clinical trial data management. Show clear roles and qualifications.
- Detail your data management and statistical systems in depth. Include cybersecurity, quality assurance, and data validation protocols.
- Align your center's proposed services directly with current autoimmune disease research priorities. Review recent NIH strategic plans on autoimmune diseases.
- Provide letters of support from potential research sites or networks you would serve. Demonstrate demand for your coordinating services.
⚠️ Common mistakes
Underestimating the complexity of multi-site data management and statistical support required. Proposals lack detail on specific systems, quality assurance, or staff expertise. Many applicants fail to demonstrate prior experience successfully coordinating large clinical research networks or managing sensitive health data at scale.
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